Our nails are surprisingly vulnerable. A number of conditions and injuries can damage them, including fungal infections, psoriasis, and physical trauma.
That’s where urea nail gel comes in. This topical keratolytic emollient is designed to soften and remove hyperkeratotic (thickened) nail tissue while helping to increase moisture in the nail and surrounding skin.
If you’re intrigued by what urea nail gel is used for, then you’ve come to the right place. This article provides a comprehensive overview of its uses, benefits, and precautions so you can decide if it’s right for you.
What is Urea Nail Gel?
Urea nail gels are topical treatments for nail problems, particularly those involving thickened, hard, or fungal-infected nails. The active ingredient in these gels is urea, a diamide of carbonic acid, typically at a concentration of 40% to 45%.
Besides urea, these gels often include other ingredients with soothing or antiseptic properties, such as:
- Camphor
- Eucalyptus oil
- Menthol
- Propylene glycol
How it Works
Urea is a keratolytic, meaning it gently dissolves the connections between cells. This action helps soften and shed areas of the nail that are thick or overgrown.
Urea also has emollient properties. It increases moisture by softening keratin, a key structural protein in nails. This softening action improves hydration and overall nail health.
What is urea nail gel used for?
Urea nail gel is a topical medication with a few different uses. It’s important to use it correctly to get the most benefit and avoid side effects.
Treatment of nail conditions
Urea nail gel is often used to soften and remove damaged portions of a nail. For example, it can help with:
- Thickened nails
- Overgrown nails
- Ingrown nails
The urea helps to break down the damaged nail tissue, making it easier to trim or remove. This can promote healing of the nail bed.
Treatment of skin conditions
Urea is also used to treat skin conditions that cause a buildup of thick, dry skin, such as:
- Dry skin
- Dermatitis
- Psoriasis
Urea can also help with wound healing in some cases.
Off-label uses
Sometimes, doctors prescribe urea nail gel for conditions other than those listed in the official prescribing information. Always follow your doctor’s instructions when using any medication, including urea nail gel.
How to use urea nail gel
If your doctor prescribes urea nail gel, it’s important to follow their instructions to get the best results.
Generally, you’ll want to apply a thin layer of the gel to the affected nail, being careful to avoid getting it on your cuticles or the skin around your nail. Allow the gel to dry completely. Your doctor may tell you to cover the nail with a bandage. If so, be sure to follow those instructions.
You will likely need to apply the gel twice a day, or as your doctor directs.
General precautions
- Urea nail gel is for external use only.
- Keep it away from your eyes, lips, and any mucous membranes.
- Unless you are using it to treat the skin on your hands, be sure to wash your hands after you apply the gel.
Potential Side Effects and Warnings
Like any medication, urea nail gel can cause side effects.
Common Side Effects
When you first begin to use urea nail gel, you may notice temporary stinging, burning, itching, or irritation around the application site. This is common and usually resolves as your body adjusts to the medication.
However, if these symptoms persist, worsen, or cause significant discomfort, it’s important to contact your doctor or dermatologist. They can assess the situation and determine if any adjustments to your treatment plan are necessary.
Serious Side Effects
Although rare, allergic reactions to urea nail gel are possible. Seek immediate medical attention if you experience any signs of an allergic reaction, such as:
- Hives
- Difficulty breathing
- Swelling of the face, lips, tongue, or throat
It’s also crucial to report any unusual skin changes, signs of infection (such as increased redness, swelling, or pus), or other concerning symptoms to your doctor promptly. Early detection and treatment can help prevent complications.
Warnings and Precautions
Before using urea nail gel, it’s essential to discuss your medical history with your doctor, particularly if you have any pre-existing skin conditions, such as cuts or infections in the treatment area. In addition, some urea nail gel products may increase your skin’s sensitivity to the sun. Take appropriate sun protection measures, such as wearing protective clothing and using sunscreen, while using these products.
Drug interactions and other things to know
Drug interactions
It’s always a good idea to have a conversation with your doctor or pharmacist about any medications you’re taking, including over-the-counter medicines, supplements, and herbal remedies, before you start using a new product.
Pregnancy and breastfeeding
If you’re pregnant or breastfeeding, talk with your doctor before using urea nail gel. Some products are considered pregnancy category B, while others fall into category C.
Experts also don’t know whether urea passes into breast milk, so get medical advice before using it if you’re nursing.
Overdose
Don’t swallow urea nail gel. It can be harmful.
If someone accidentally swallows it, get medical help right away.
Frequently Asked Questions
What does urea gel do to nails?
Urea gel, often used in nail treatments, acts as a keratolytic agent. This means it helps to soften and break down keratin, the main protein in nails. This softening effect allows for better penetration of other medications, easier trimming of thick or brittle nails, and improved hydration.
When should you not use urea cream?
Avoid urea cream if you have a known allergy to urea or any of the other ingredients in the product. It’s also generally not recommended for use on open wounds, infected skin, or severely irritated areas without consulting a doctor. If you experience a burning sensation or rash, discontinue use.
What does urea do to feet?
Urea is a powerful humectant and keratolytic, making it beneficial for treating dry, cracked, and calloused feet. It helps to draw moisture into the skin while simultaneously breaking down hardened skin cells, leaving feet feeling softer and smoother. It’s a common ingredient in foot creams.
How long does it take for urea cream to soften toenails?
The time it takes for urea cream to soften toenails varies depending on the concentration of urea and the thickness of the nails. Generally, with consistent daily application, you might notice a difference within a few weeks. Severely thickened nails may require several months of treatment.
How do you apply urea to your toenails?
Apply a thin layer of urea cream or gel directly to the affected toenails, ensuring the entire nail surface is covered. Gently massage it in. For best results, apply after showering or soaking your feet when the nails are more hydrated. You can also cover the treated nails with socks or bandages to enhance absorption.
Conclusion
Urea nail gel is a topical medication that can treat nail and skin problems, especially when the problem involves hyperkeratosis, or the thickening of skin and nails. It’s often used to treat fungal infections, damaged or ingrown nails, and other conditions that cause thick, rough, or scaly skin or nails.
It’s important to follow a doctor’s instructions when using urea nail gel. When you use it the right way, urea nail gel can be a helpful tool for restoring the health of your nails.