Urea Nail Gel 45% Guide: Benefits, Side Effects & How to Use

Urea Nail Gel 45% is a topical ointment used on the skin and nails to soften them, which can address certain nail problems. It’s a keratolytic emollient, which means it helps to break down the protein keratin, which is what makes up skin and nails.

This article will give you a complete overview of Urea Nail Gel 45%, explaining what it’s used for, what precautions you should take, and what side effects you might experience.

What is urea nail gel 45%?

Urea nail gel 45% is a topical treatment designed to help soften and remove damaged or diseased nail tissue.

What’s in it?

The active ingredient is 45% urea, which works as a keratolytic, meaning it breaks down the tough outer layer of skin or nails.

The inactive ingredients in most formulations include things like:

  • camphor
  • edetate disodium
  • eucalyptus oil
  • hydroxyethyl cellulose
  • menthol
  • propylene glycol
  • purified water

How does it work?

Urea works by gently dissolving the connections between cells. This helps to soften and shed areas where the skin or nails have become too thick.

Urea also has emollient properties, which means it helps to hydrate and soften the skin and nails.

Indications and Usage

Urea 45% nail gel is FDA-approved to help with removing dead tissue and encouraging healing in thick, crusty skin.

Doctors may recommend this gel for:

  • Dry skin
  • Dermatitis
  • Psoriasis
  • Damaged nails

It’s important to use urea nail gel exactly as your doctor instructs you to.

Precautions and warnings

Like any medication, you’ll want to use urea nail gel 45 with care.

General precautions

  • For external use only. Don’t get it in your eyes, on your lips, or on any sensitive tissue.
  • Stop using urea nail gel 45 if you notice redness, irritation, or other signs of a reaction.

Pregnancy considerations

Animal studies haven’t shown any evidence of harm, but research on humans is limited.

If you’re pregnant, talk with your doctor about whether urea nail gel 45 is right for you.

Potential Side Effects and Adverse Reactions

Like any topical treatment, urea nail gel can cause side effects. Most are mild, though, and resolve on their own.

  • Common side effects: Some people experience temporary stinging, burning, itching, or irritation.
  • When to seek medical attention: If irritation gets worse or doesn’t go away, talk to your doctor.

Dosage and administration

If you’re using a urea nail gel or cream, here’s what you need to know about how to apply it:

  • Apply twice daily, unless a doctor tells you otherwise.
  • Always follow the directions of your healthcare provider when using this product.

Frequently Asked Questions

When should you not use urea cream?

While generally safe, you shouldn’t use urea cream if you have open wounds, cuts, or severely irritated skin in the application area. Also, avoid it if you’re allergic to urea or any of the other ingredients in the cream. Always consult a doctor if you’re unsure.

Should I cut my toenail off if it has fungus?

No, you should not attempt to cut off a toenail infected with fungus. This can lead to further complications, such as infection or ingrown toenails. See a podiatrist or doctor for proper diagnosis and treatment options. They might recommend antifungal medications or professional nail trimming.

What does urea 40% do to toenails?

Urea 40% acts as a keratolytic, meaning it helps to soften and dissolve keratin, the protein that makes up your nails, which can be helpful in differentiating nail dystrophy from onychomycosis. This can help thin thickened nails, making them easier to manage and allowing antifungal medications to penetrate more effectively. It also hydrates the nail.

What does 47% urea gel do?

A 47% urea gel, similar to the 40% concentration, works by softening and loosening the damaged or thickened parts of the nail. The slightly higher concentration may offer a more potent effect, helping to remove dead tissue and improve the appearance of the nail. It’s also a moisturizer.

What is urea gel used for?

Urea gel is primarily used to treat thickened, dry, and damaged nails, often associated with fungal infections or psoriasis. It helps soften the nail, making it easier to trim and allowing for better absorption of other medications. It’s also used to hydrate the nail bed and surrounding skin.

The takeaway

Urea Nail Gel 45% is a topical product used to treat nails affected by thickening or excess keratin. It’s important to use Urea Nail Gel 45% as directed by your doctor to ensure you’re using it safely and getting the best results.